The eponymous inn was originally constructed as a cottage in 1719 by the Welsh Quakers William and Janet Rees, founders of nearby Reeseville. The cottage was converted to an inn in 1769 and did a steady business in colonial times as it was approximately a day’s travel by horse from Philadelphia. King of Prussia has retained its role as an important crossroads throughout United States history. In addition to the Inn, from the earliest days, the intersection supported two general stores.

Today, four major highways meet in or near the center of King of Prussia. The Schuylkill Expressway (I-76) from Center City, Philadelphia, ends in King of Prussia at the Pennsylvania Turnpike, an east-west toll road across the southern portion of the state. US 422 begin near the center of town and heads west to Reading; thanks to reconstruction in 2000, motorists can now travel directly from Reading to Philadelphia without passing onto US 202. US 202 are the only major highway that becomes a surface road through the area. The construction of one of the nation’s largest shopping malls, thousands of homes, various hotels and high-rises, strip malls, restaurants, freeways, a convention center, and much more has caused King of Prussia to become a highly developed community.

King of Prussia is home to the King of Prussia Mall, the largest shopping complex in the United States, based on shopping area square footage. (The Mall of America in Bloomington, Minnesota, is the largest when theme park square footage is included.) King of Prussia comprises two malls which are connected by a short covered crosswalk.